Model NO.: 87616-84-0
Trademark: YCGC
Origin: China
HS Code: 12345677
Model NO.: 87616-84-0
Trademark: YCGC
Origin: China
HS Code: 12345677
Basic InformationSynonyms: GHRP-6
CAS NO.: 87616-84-0
Molecular Formula: C46H56N12O6
Molecular weight: 873.01
Molar Mass: 873.014
Peptide purity: >Â 98.0%
PubChem: 5486806
Appearance: White lyophilized powder
Related substance: Total Impurities (%) ≤ 2.0%
Acetate content: ≤ 15.0%
Bacterial Endotoxins: ≤5 IU/mg
Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Source: Chemical Synthesis
Reconstitution: To follow best practice guidelines for reconstituting GHRP-6, reconstitute in sterile, bacteriostatic, distilled water, with light sonication if necessary.
Storage of GHRP-6: Lyophilized GHRP-6 although stable at room temperature for 3 weeks, should be stored desiccated below -20°C.Upon reconstitution GHRP-6 should be stored at 2-8°C between 2-7 days and for future use below -20°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Shelf life: One year from dispatch.
Description
Follistatin is a secreted glycoprotein that was first identified as a follicleÂstimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an NÂterminal atypical TGF binding domain, three Follistatin domains that contain EGF Âlike and kazalÂlike motifs, and a highly acidic CÂterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.
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It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH. In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene.Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals.Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
Applications
Follistatin 315 is a naturally occurring human peptide and a potent inhibitor of myostatin. Myostatin encourages the degradation of myotubes therefore inhibition of myostatin will ultimately result in increased muscle mass by preventing degradation.Follistatin is being studied for its role in regulation of muscle growth, as an antagonist to myostatin.
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Either by genetic elimination or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy in animal models.
Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
Our advantage
a.Rich experience.We are a professional manufacturer in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation.
b.Great quality,purity and competitive price.Different country with different and suitable way of packing.Packing pictures will be sent to you as soon as possible after your payment.
c.Safe and fast delivery.We will send you with a safest and most suitable channel.
d.Good after-sales service.Our purpose is to hold a long friendly cooperation with our customers,so we will offer you best service from start to finish.
 Basic Information
Synonyms: GHRP-6
CAS NO.: 87616-84-0
Molecular Formula: C46H56N12O6
Molecular weight: 873.01
Molar Mass: 873.014
Peptide purity: >Â 98.0%
PubChem: 5486806
Appearance: White lyophilized powder
Related substance: Total Impurities (%) ≤ 2.0%
Acetate content: ≤ 15.0%
Bacterial Endotoxins: ≤5 IU/mg
Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Source: Chemical Synthesis
Reconstitution: To follow best practice guidelines for reconstituting GHRP-6, reconstitute in sterile, bacteriostatic, distilled water, with light sonication if necessary.
Storage of GHRP-6: Lyophilized GHRP-6 although stable at room temperature for 3 weeks, should be stored desiccated below -20°C.Upon reconstitution GHRP-6 should be stored at 2-8°C between 2-7 days and for future use below -20°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Shelf life: One year from dispatch.
Description
Follistatin is a secreted glycoprotein that was first identified as a follicleÂstimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an NÂterminal atypical TGF binding domain, three Follistatin domains that contain EGF Âlike and kazalÂlike motifs, and a highly acidic CÂterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.
Â
It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH. In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene.Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals.Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
Applications
Follistatin 315 is a naturally occurring human peptide and a potent inhibitor of myostatin. Myostatin encourages the degradation of myotubes therefore inhibition of myostatin will ultimately result in increased muscle mass by preventing degradation.Follistatin is being studied for its role in regulation of muscle growth, as an antagonist to myostatin.
Â
Either by genetic elimination or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy in animal models.
Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
Our advantage
a.Rich experience.We are a professional manufacturer in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation.
b.Great quality,purity and competitive price.Different country with different and suitable way of packing.Packing pictures will be sent to you as soon as possible after your payment.
c.Safe and fast delivery.We will send you with a safest and most suitable channel.
d.Good after-sales service.Our purpose is to hold a long friendly cooperation with our customers,so we will offer you best service from start to finish.
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