A large-scale genetic study published online by the British journal Nature Genetics on the 23rd said that the international team of scientists launched a survey covering 1 million people and found genetic variants related to education levels. They found more than 1,200 related genetic variants in large samples, more than ten times the number of genetic loci found in previous studies. Candidate genes in this study have been shown to play important roles in brain development and neuronal information communication.
The "status" of some genetic variants plays an important role in affecting people's thinking, learning skills and personality traits. But how much does a person's genes directly affect how far they go on the road to education? The debate on this issue has been around for a long time. In a study earlier, Daniel Benjamin of the University of Southern California and a group of international scientists found that multiple genes in the body were more likely to be mutated than those with lower education. . However, scientists are still unclear about the specific impact of the overall environment and genetic factors on education, and the underlying mechanisms of action.
This time, an international research team composed of scientists from the University of Southern California, the Free University of Amsterdam, and the University of Queensland, Australia, conducted an investigation into the genetic makeup and educational background of more than 1 million people. In the large sample study, the research team discovered more than 1,200 genetic variants associated with educational duration. The research team also analyzed the test scores of each subject, the self-reported mathematics ability, and the highest level of mathematics education to identify hundreds of genes associated with these traits.
The analysis found that genetic mutations related to education first appeared in the core region that controls brain development, and the expression levels of related genes in the brain increased, and also on neurotransmitter secretion and synaptic plasticity. The researchers believe that this large library of related gene loci can be further used to study the effects of genetic and environmental interactions on cognitive phenotypes.
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