DNA nanobots that recognize and sort molecules are born!

[ China Pharmaceutical Network Technology News ] Micro-robot made of DNA, capable of sorting and transporting molecular cargo. For the introduction of this DNA robot, Wenlong Cheng, a nano-bionic researcher from Monash University in Australia, said, "The application of this technology is very promising. The first benefit will be the delivery of targeted drugs."

(DNA nanobots that recognize and sort molecules are born!)

Lei Feng.com recently published a new study by the famous magazine Science. The Chinese scientist Qian Qi from California Institute of Technology and the DNA robot developed by his team were born. This micro-robot made of DNA has the ability to sort and transport molecular cargo. Qian Wei’s team researchers said that such DNA robots can not only identify and sort different fluorescent molecules, but also transport target molecules to special locations “unloading”. When multiple robots work together, the accuracy is closer. 100%.

"Imagine that electromechanical robots are sent to places where humans cannot reach, such as Mars," said Qian Wei, the inventor of DNA robots. "We hope that one day we can send DNA robots to blood and other tiny places that humans cannot reach."

A small step in DNA nanobots is a big step for humans.

According to Lei Feng.com, the DNA robot consists of three basic modules: a "leg" and two "foot". These two parts are used for walking. One "arm" and one "hand" are used for sorting. And the "signal" of the carrier, and a "signal" that indicates the "goods" after arriving at the designated location. And each of these modules is a short piece of DNA.

How exactly does the DNA robot walk?

Only a DNA robot with a single-strand structure is more like a swaying spring during walking, or like a creeping caterpillar.

However, according to the principle of base pair matching of nucleotides, A (adenine, adenine), T (thymine, thymine), C (cytosine, cytosine), G (guanine, guanine) can be connected in pairs, thereby Forming a double-stranded structure is the basis for DNA robots to walk.

In the experiment, the scientist's robot walked on a 58 x 58 nm nail plate made of DNA origami. Anupama Thubagere, a bioengineer and lead author of the California Institute of Technology, said, "Each plate is connected by a large string of DNA to form a piece of DNA."

The research team designed the DNA robot's legs and feet to the required length. For example, in the experiment, the researchers designed it to be 6 nanometers. Usually only a few percent of the human step size.

In addition, in the experiment, the researchers also dispersed two different pigments in different areas of the molecular surface, and then they let the DNA robot collect molecules that are free in space and carry the molecules to their original positions.

The results showed that the DNA robot successfully placed the free molecules in situ within 24 hours, three pinks and three yellows, respectively, with no errors. In this regard, the research team said that if more DNA robots are used, the time to complete the task will be greatly shortened.

Where is the future application of DNA robots going?

For the introduction of this DNA robot, Wenlong Cheng, a nano-bionic research scholar from Monash University in Australia, said, “The application of this technology is very promising. The first benefit will be the delivery of targeted drugs,” he explained. "If the patient has a tumor, this tiny robot can even complete the positioning and operate a small 'surgery'."

Professor John H. Reif from Duke University commented in the magazine Science, "The most outstanding contribution of this research is that they can make multiple simple DNA devices perform non-trivial tasks at the same time. This means Soon this technology will be applied in chemical synthesis and nanomedicine, which is worth our expectation."

According to Lei Feng.com, Qian’s attitude is objective and calm. She said: “We will not develop DNA robots for any specific scenario. The goal of the lab is to develop a universal DNA robot. However, I hope Other researchers can use this technology for practical production applications, such as using DNA robots to synthesize therapeutic chemicals from components of man-made molecular plants, or sorting molecular components in waste for recycling."

Original title: DNA nanobots that recognize and sort "molecules" come in, which transport drugs to human blood

Teach you to use APP (Pharmaceutical Pass) to seize business opportunities

Coin-operated Safe


A coin-operated safe is a secure storage device that requires the insertion of a specific denomination of coin in order to unlock and access its contents. It is typically used in public settings such as laundromats, locker rooms, or amusement parks, where individuals may need a temporary storage solution for their valuables.


The coin-operated safe is constructed with durable materials such as steel to ensure its resistance to tampering or forced entry. It features a coin slot on the front panel, where users insert the required coin to initiate the unlocking mechanism. Once the coin is inserted, the safe's door can be opened to reveal the storage compartment.


The size of the coin-operated safe may vary depending on its intended use. Some models are designed to hold small personal items like wallets, keys, or mobile phones, while others are larger and can accommodate larger items like bags or jackets.


To ensure security, the safe is equipped with a robust locking mechanism that engages once the door is closed. This prevents unauthorized access and provides peace of mind for users. Additionally, many coin-operated safes have additional security features such as electronic locks, combination locks, or key locks to further enhance protection.


Small Coin-Operated Safes,Coin Cash Safe Box With Drawer,Steel Coin-operated Safe,digital code coin safe

Hebei Hupai Aodi Cabinet Industry Co.,Ltd. , https://www.aodicabinet.com

Posted on