Scholars at the Moscow Institute of Engineering Physics at the National University of Nuclear Research in Russia have developed a new contrast agent for magnetic resonance imaging (MRT) based on silicon nanoparticles, which can be used to diagnose and treat tumor diseases at the same time. The findings were published in the Journal of Applied Physics.
Professor Viktor Tymoshenko, a professor at the School of Biomedical Engineering Physics and a professor at Moscow's Lomonosov National University, said the latest study is a classic example of nanodiagnostic therapy – combining nanoscale diagnostics and treatments.
Nanoparticles cannot accumulate in the body and their surface should not be contaminated. Therefore, materials for nanodiagnostic therapy should be non-toxic, compatible with the human body, and able to “escape†the immune system.
Representatives of the Institute's “Nano-Diagnostic Therapy†lab believe that the use of silicon nanoparticles to detect damaged cells is one of the most promising methods for treating cancer using nanodiagnostic therapy. The nanoparticles themselves are harmless to the body, but can be heated to about 42 degrees Celsius or higher (called hyperthermia) under the action of radio waves, which ensures local killing of cancer cells.
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