[China Pharmaceutical Network Technology News] The immortality has always been the pursuit of mankind, but from a scientific perspective, many people believe that this can not be achieved, but if it is to extend life? The team of scientists at University College London gave the answer, identifying a protein that causes us to age, namely GSK-3 (glycogen synthase 3). In an experiment with Drosophila, scientists found that GSK-3 protein can be shut down by low doses of lithium. As a result, scientists found that the lifespan of fruit flies increased by a staggering 16%. 
Lithium is fatal to humans and carries some additional side effects such as nausea, diarrhea, dizziness, muscle weakness and fatigue, so scientists are likely to look for alternatives that have the same effect. In addition, a better understanding of this protein can also help scientists deal with senile diseases such as Alzheimer's and Parkinson's.
Dr. Jorge Ivan Castillo-Fu of Harvard University worked at University College London, where he was the lead author of the study. He claims: "The discovery of GSK-3 is very exciting for us. This may mean that if this study allows us to get a new treatment, all age-related diseases may be prevented in the near future."
He said: "I think this research has a more exciting future than extending life. There are many people who are arguing over the study of life extension, but it is also related to the extension of health. For example, if this drug It is great to be able to delay Alzheimer's disease from 75 to 90. We don't want to live to 110 or 120, but we want a longer healthy life."
The research has been helped by scientists from the Bio-Aging Research Department of the Mark Planck Institute and the European Molecular Biology Laboratory. The next step in the research will be to explore how to manipulate GSK-3 protein in small mammals such as mice. Subsequent studies of classes and humans will also follow.
Lithium is fatal to humans and carries some additional side effects such as nausea, diarrhea, dizziness, muscle weakness and fatigue, so scientists are likely to look for alternatives that have the same effect. In addition, a better understanding of this protein can also help scientists deal with senile diseases such as Alzheimer's and Parkinson's.
Dr. Jorge Ivan Castillo-Fu of Harvard University worked at University College London, where he was the lead author of the study. He claims: "The discovery of GSK-3 is very exciting for us. This may mean that if this study allows us to get a new treatment, all age-related diseases may be prevented in the near future."
He said: "I think this research has a more exciting future than extending life. There are many people who are arguing over the study of life extension, but it is also related to the extension of health. For example, if this drug It is great to be able to delay Alzheimer's disease from 75 to 90. We don't want to live to 110 or 120, but we want a longer healthy life."
The research has been helped by scientists from the Bio-Aging Research Department of the Mark Planck Institute and the European Molecular Biology Laboratory. The next step in the research will be to explore how to manipulate GSK-3 protein in small mammals such as mice. Subsequent studies of classes and humans will also follow.
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