In vitro diagnostic techniques have developed rapidly over the past few years, from gene-level gene sequencing , SNP screening, point-and-mutation gene diagnosis, to protein level biomarker detection, to cell-level circulating tumor cell detection (CTC). , thin-layer liquid-based cytology (TCT), and then PET/CT at the tissue level. Also hotter recently is the report that a single drop of blood can detect multiple disease indicators. In general, in vitro diagnostics are moving toward simpler, faster, non-invasive, and more informative. For human health, I think in vitro diagnostics work in the following ways:
In vitro diagnosis for the first disease prevention
"The Yellow Emperor's Internal Classics" has a cloud: "It is because the saints have not cured the disease and have not been cured. If the disease has not been treated, it will be chaotic. This is also the case. The disease has become a cure for the disease, and the chaos has become a cure. And wearing a well, fighting and casting a cone, not too late." This sentence puts forward the idea of ​​"treatment of disease" and clarifies the importance of "treatment of disease." Modern people are paying more and more attention to their own health. Many people have become a habit every year, and unit medical examination has become a necessary employee welfare. The main purpose of the physical examination is to prevent and early detection of the disease, and in vitro diagnosis has a very large market in this field, using the provided blood, urine, feces, body fluids, secretions, etc. to complete the test.
In vitro diagnosis for chronic disease management
The incidence of diabetes in the world has increased rapidly. The number of diabetic patients in developed countries has reached more than 10%. The number of diabetic patients in China has exceeded 4%, and the number of developed areas has reached 6%, showing an upward trend. In recent years, the incidence of hypertension in China has increased year by year. The data show that there are more than 100 million patients with hypertension in China. According to statistics, the average incidence of hypertension in people over 15 years old is 11%. The stomach disease has become an extremely common disease in life. According to the statistics of the World Health Organization in recent years, The incidence of stomach diseases in China is as high as 80% or more, that is, 8 out of every 10 people suffer from stomach diseases. There is also a high incidence of these diseases such as hyperlipidemia and osteoporosis. These diseases are characterized by chronic diseases. Regular monitoring of blood sugar, blood pressure, blood lipids, Helicobacter pylori, changes in bone calcium, and in vitro diagnostics have corresponding equipment. In particular, there are various mobile wearable devices that can monitor blood sugar, blood pressure, heart rate, etc. anytime and anywhere.
In vitro diagnosis for the monitoring of severe disease prognosis
Many cancer patients undergo surgery, and tumor markers are regularly monitored after radiotherapy and chemotherapy to predict cancer metastasis and to guide medication. Such as breast cancer patients should be regularly performed chest X-ray, bone scan, liver B-ultrasound, blood routine, tumor-related antigen examination. As breast cancer patients progress, the spread and metastasis of systemic cancer cells may occur, and the brain metastasis of cancer cells is the most deadly. Breast cancer often has a very poor prognosis after brain metastases, which may lead to death within a few months. Bio Valley has reported that researchers from the British Columbia Cancer Research Center used αB-crystallin gene expression as an indicator of cancer cell metastasis, and also as an important evaluation of patient prognosis, independent of other clinical biochemical indicators. This clinical data analysis of 4,000 breast cancer patients found that breast cancer patients with high expression of αB-crystallin gene in the brain were three times or more higher than breast cancer patients with low gene expression (negative results). Cancer cell brain metastasis risk.
With the constant breakthroughs in biotechnology, I believe there will be more and more sensitive in vitro diagnostic methods appear at the same time, the state strongly support the biotechnology industry, their status as one of the state's key support industries; new health care reform continue Advance to the grassroots level, in order to reduce the medical expenses of residents and improve medical efficiency, disease prevention and diagnosis should be strengthened; with the increase in income, people put forward higher requirements for health and medical quality. Therefore, in this environment, the development of the in vitro diagnostic industry will usher in a golden age.
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