Copper peptide GHK-Cu is a naturally occurring copper complex of a glycyl-L-histidyl-L-lysine peptide. Since it has three amino acids it is called tripeptide. The GHK-Cu tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine.
Copper peptides are naturally occurring small protein fragments that have high affinity to copper ions. In human plasma, the level of GHK-Cu is about 200 µg/ml at age 20. By the age of 60, the level drops to 80 µg/ml. In humans, tripeptide GHK-Cu can promote activation of wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen andglycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth. Recent studies revealed its ability to modulate expression of a large number of human genes, generally reversing gene expression to a healthier state. Synthetic GHK-Cu is used in cosmetics as a reparative and anti-aging ingredient.
In the late 1980s, copper peptide GHK-Cu started attracting attention as a promising wound healing agent. Pioneers in this field were J.P Borel and F. Maquart from Université de Reims Champagne-Ardenne (France). At optimal, picomolar to nanomolar concentrations, GHK-Cu stimulated the synthesis of collagen in skin fibroblasts, increased accumulation of total proteins, glycosaminoglycans (in a biphasic curve)and DNA in the dermal wounds in rats. They also found out that the GHK sequence is present in collagen and suggested that the GHK peptide is released after tissue injury. They proposed a class of emergency response molecules which are released from theextracellular matrix at the site of an injury.[12] GHK-Cu also increased synthesis of decorin - a small proteoglycan involved in the regulation of collagen synthesis, wound healing regulation and anti-tumor defense.
The same group established that GHK-Cu stimulated both the synthesis of metalloproteinases, the enzymes which break down dermal proteins, and their inhibitors (anti-proteases). The fact that GHK-Cu not only stimulates the production of dermal components, but also regulates their breakdown suggests that it should be used with caution.
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Copper peptide GHK-Cu is a naturally occurring copper complex of a glycyl-L-histidyl-L-lysine peptide. Since it has three amino acids it is called tripeptide. The GHK-Cu tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine.
Copper peptides are naturally occurring small protein fragments that have high affinity to copper ions. In human plasma, the level of GHK-Cu is about 200 µg/ml at age 20. By the age of 60, the level drops to 80 µg/ml. In humans, tripeptide GHK-Cu can promote activation of wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen andglycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth. Recent studies revealed its ability to modulate expression of a large number of human genes, generally reversing gene expression to a healthier state. Synthetic GHK-Cu is used in cosmetics as a reparative and anti-aging ingredient.
In the late 1980s, copper peptide GHK-Cu started attracting attention as a promising wound healing agent. Pioneers in this field were J.P Borel and F. Maquart from Université de Reims Champagne-Ardenne (France). At optimal, picomolar to nanomolar concentrations, GHK-Cu stimulated the synthesis of collagen in skin fibroblasts, increased accumulation of total proteins, glycosaminoglycans (in a biphasic curve)and DNA in the dermal wounds in rats. They also found out that the GHK sequence is present in collagen and suggested that the GHK peptide is released after tissue injury. They proposed a class of emergency response molecules which are released from theextracellular matrix at the site of an injury.[12] GHK-Cu also increased synthesis of decorin - a small proteoglycan involved in the regulation of collagen synthesis, wound healing regulation and anti-tumor defense.
The same group established that GHK-Cu stimulated both the synthesis of metalloproteinases, the enzymes which break down dermal proteins, and their inhibitors (anti-proteases). The fact that GHK-Cu not only stimulates the production of dermal components, but also regulates their breakdown suggests that it should be used with caution.
WHY CHOOSE OUR FILTER?
1. GMP manufacturer |
2. Competitive price and high quality |
3. A powerful peptide manufactory |
4.25years Years of experience in the pharmaceutical and good reputation. |
5. Secure shipping and delivery guaranteed. |

Licorice extract is a medicinal ingredient extracted from licorice. Licorice extract generally contains glycyrrhizin, glycyrrhizic acid, glycyrrhizin, glycyrrhizin flavonoids, glycyrrhizin, etc., which is yellow to brownish yellow powder.
Licorice extract is an ideal antioxidant and preservative in the food industry. It can also be used as food additive, flavoring, sweetener, tobacco, cigar, chocolate, beer, vanilla, sweet wine and other flavors.
Licorice extract can be used as cosmetic additive, anti-inflammatory, prevention and treatment of hand and foot chapping and frostbite, can be used in creams, milk and other cosmetics. The soluble components of liquorice in medium polar solvent (ethyl acetate, chloroform, ether) have significant effects on hair maintenance and hair protection.
Licorice Flavonoids,Licorice Root Extract,Glabridin,Glycyrrhizin,Dipotassium Glycyrrhizinate
Xi'an Gawen Biotechnology Co., Ltd , https://www.amextract.com