"Lancet" research results confirm that China's program to solve the cardiovascular world problem
September 06, 2018 Source: China News Network
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Beijing time on September 4 (British time on the evening of September 3, 2018), the world's top authoritative medical magazine "The Lancet" (The Lancet) full-text published China's self-developed Firehawk (Fire Eagle) coronary rapa The results of a large-scale clinical trial (TARGET AC) in the European-targeted eluting stent system (hereafter referred to as the Fire Eagle stent) have solved the major problems that have plagued the world's cardiovascular intervention field for more than 10 years.
This is the first time in the past 200 years that the "Lancet" has appeared in China's medical devices. It marks that the Chinese company's fully independent research and development of the Fire Eagle stent has become the new standard for the new generation of heart stent industry in the world. The company is Shanghai Wei Chuang Medical Devices (Group) Co., Ltd. founded by Zhang Zhaohua in Shanghai Zhangjiang in 1998.
This issue of The Lancet focuses on the clinical research conducted by the Firehawk Stent in 21 hospitals in 10 countries in Europe from December 2015 to October 2016, demonstrating the design of micro-packaged targeted elution. The featured Fire Eagle stent achieves the highest level of efficacy with the lowest dose and minimal side effects of all drug stents in the world. It also combines the safety advantages of bare stents with the more effective advantages of drug stents, achieving the highest efficacy. The anti-conventional practice of pursuing the minimum dose.
At present, the traditional mainstream cardiac stent brands use drugs on the surface of bare metal stents to continuously expand blood vessels, and there are major risks such as postoperative complications, heavy medical burden and huge psychological pressure.
The Fire Eagle stent uses a unique laser single-sided groove coating technology and targeted elution technology, and its drug loading capacity is the lowest in the world, less than 1/3 of other stents can achieve the same effect; and the fire eagle stent manufacturing process is subtle Extremely, it is necessary to evenly dig up nearly 600 grooves on a cobalt-chromium alloy that is as thin as a hair but extremely hard, to avoid applying the medicine on the ineffective surface (inner wall), which not only achieves the efficacy of the common drug stent, but also maintains the metal. Long-term safety of bare stents.
In order to accurately inject the drug into these micro-grooves, Mini-Chuang has also independently developed a unique drug-coating equipment, fully automatic three-dimensional printing micro-groove filling, which can control the error to the micron level, and the area of ​​the drug coating only accounts for metal. Covering 20% ​​of the area.
With the Fire Eagle stent in the ten countries of Europe, it has been listed or registered in 36 countries and regions around the world. Professor Ferdinand Kiemeneij, a well-known Dutch cardiovascular intervention specialist who is known as the “father of transradial interventional therapyâ€, was the first doctor to use the Fire Eagle stent in Europe to complete the operation. He praised the Fire Eagle stent as the most promising new generation stent. Professor Patrick W. Serruys, a world-renowned cardiologist and the King's College of the United Kingdom, pointed out: "Advances in the development of interventional devices from Asia have profoundly affected the European and American markets. In the future, innovation in medical devices in Asia will lead the industry trend."
As of the end of 2017, approximately 4.5 million coronary products including the Fire Eagle stent have been treated by the minimally invasive treatment of approximately 3.5 million patients worldwide. In addition, the second generation of biodegradable drug scaffolds independently developed by Minimally Invasive has entered the clinical stage, and clinical safety and effective verification have achieved good results.
Chang Zhaohua felt that at the beginning of the development of the product, he believed that this forward-looking treatment concept characterized by low-dose drug elution would surely achieve world-renowned scientific and technological achievements. He did not expect the resource input intensity to be so high, and the process was so tortuous. Several generations of R&D teams have been through the hardships of 15 years. It is hoped that with the large-scale promotion and use of the Fire Eagle stent in the world, especially in China, its performance and efficacy can help boost the confidence and goodwill of Chinese people on domestic medical products. Science and technology workers need a society that is confident in independent innovation. surroundings. Based on this, the future will continue to be based on “scientific and technological innovationâ€, based on evidence-based medicine, allowing clinical data to speak, and by developing a community of fate with patients and doctors, to develop more global medicine like the Firehawk stent. The high-end medical products that the community and patients trust, or the revolutionary medical programs that provide treatment for various chronic diseases, contribute to satisfying the endless pursuit of “health and longevityâ€. â€
It is worth mentioning that the review period of the article published in The Lancet is usually several months or even one or two years, but this Lancet took only three weeks from the time of receiving the submission to making the publication. And five peer reviewers made positive and positive feedback. (Reporter Xu Wei)
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