Breaking traditional B cells can prevent premature birth

Breaking traditional B cells can prevent premature birth

January 04, 2017 Source: Bio Valley

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The proportion of premature babies in the United States and many other countries has risen to 1/6, which is the leading cause of infant deaths and long-term illnesses, with a heavy social and economic burden. A new study by Nature, a research team led by Dr. Kang Chen, an associate professor at Wayne State University School of Medicine, found that mother's B lymphocytes play an important role in resisting inflammation and triggering preterm birth.

Scientists and clinicians have previously believed that there are no B cells in the endometrium, so it is considered that B cells are not important for pregnancy. However, Chen's research indicates that late pregnancy B cells not only exist in human and mouse endometrium, but also can induce uterine pressure and infection (the main cause of premature birth), and generate some molecules to inhibit uterine infection and prevent premature birth. An important molecule is called PIBF1.

"This study not only reveals the long-neglected role of B cells in maintaining fetal health, but also provides a means to prevent or treat preterm birth using B-cell-derived molecules such as PIBF1," says Chen.

Chen's team has validated concepts and efficacy in animal models and patented this potential treatment with the help of Wayne State University's Office of Technology Transformation.

“Kang is really amazing. He independently summoned and led an excellent team to complete this original masterpiece, especially considering the many challenges encountered.” Chen’s collaborators gave him a high rating. The first author of the study was Bihui Huang and Azure Faucette, Wayne State University.

Fixative (dye-Fixing Agent)

Active Ingredient: Quaternary ammonium salt cationic surfactant
Chemical Name: Formaldehyde-free Fixing Agent
Chemical Family: PolyDADMAC

CAS No.: 26062-79-3


1.Formaldehyde-free Fixing Agent

2.Has no free formaldehyde,no peculiar smell,no irritation to skin, accord to eco request

[Description]:

Formaldehyde-free Fixative Color Fixing Agent is belongs to polymerization polyDADMAC, a cationic polymer. It can make up of macromolecular compound with dye, then achieve to improve soaping and rub fastness of fabrics. It can be used for color fixing for dyeing and printing of reactive dyed fabrics as cotton, linen, silk, and direct dyed fabrics.

[Specification]:

Appearance: Brownish yellow viscous liquid

Ionic character: Cationic

PH Value: 5-8 (1% aqueous solution)

Dissolution: Dissolve in cold water easily.

Composition: Special polymer compound

[Dilution Method]:

With 4-6 times the water and stir to dissolve dilution.

[Direction for Usage]:(To dilute finished product as an example)

A. Padding Process: 5-20g/L, temperature 40°C-60°C, PH Value:5-8, One-dip-one-nip or Double-dip-double-nip.

B. Dipping process: 1-4% (O.W.F), Room temperature 40°C-60°C, PH Value:5-8, bath ratio:1:8-12,Time: 20-30 min.



[Properties]:

1. Concentrated Formaldehyde-free Fixative Fixing Agent has good color fixing property, can obviously improve the dyeing or printing of fabric soaping, washing fastness and wet rubbing fastness.

2. Can be used for much of the association between dye fixation, anti fading property, does not affect the dyeing or printing of fabric vividness. No effect for the original feel, processing fabric has excellent hydrophilic.

3. Formaldehyde-free Fixative widely used for dyeing or printing of the direct, active dye fixing finishing, good fixation effect, especially for the red dye and Cuilan dyes, particularly prominent, fixation is better than the general Formaldehyde-free Fixative.

4. The dye PH value for a wide range, acid, alkali resistance, resistance to hard water, high temperature resistance, an environment-friendly products, does not contain formaldehyde.

Specifications:

Appearance: Colorless, Transparent Colloid
Viscosity: 100cps-80000cps
Solid Content: 40%min.
PH (30% solution):

3 - 7

Ionic Nature:

Cationic

Specific Gravity: About 1.1

Packaging & Shipping

Package and Storage:

  1. It is harmless, no-flammable and non-explosive, it can be stored at room temperature, it can not be placed in the sun.
  2. It is packaged in plastic drums with each containing 25kg, 210kg, 1100kg , or others according to the requirements of clients.
  3. Storage temperature: 5-30°C.
  4. The product would show slightly stratification or appear white at low temperature. There is no negative impact on the performance after mixing up.


Dye Fix Agent

Fixative,Dye-Fixing Agent,Organic Dye-Fixing Agent,Reactive Dye-Fixing Agent

Shandong Tiancheng Chemical Co., Ltd. , https://www.tianchengchemical.com

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