In 2009, with the development of non-coding RNA (ncRNA), a new class of ncRNA molecules, lncRNA, has become a hot topic in the scientific community and has gradually become an important direction in molecular biology and clinical medical research. Kang Cheng Bio and Arraystar of the United States cooperated with the Arraystar LncRNA series chip platform to launch the lncRNA expression screening service. Arraystar is a pioneer and leader in the field of lncRNA research. The company's lncRNA series of chips are based on the most comprehensive database and classic literature design, using the most advanced probe design concept, simultaneously detecting lncRNA and mRNA in biological samples, helping researchers to further Conduct lncRNA research. So far, as the sole agent of Arraystar China, Kangcheng customers have published more than 80 SCI papers using Arraystar LncRNA chips , many of which are published in top international magazines such as Cancer Cell, Mol Cell and Hepatology. LncRNA research background and its relationship with disease
New results of LncRNA in clinical medical research
LncRNA is an emerging hotspot in clinical medical research. It can regulate the expression of coding genes through different molecular biological mechanisms and participate in disease-related signaling pathways, which plays an important role in the occurrence, development and treatment of diseases. As a new class of clinical markers with biological functions, lncRNA has a very broad clinical application prospects. Using Arraystar's lncRNA chip, in recent years, domestic and foreign scholars have published a series of high-level research papers to help us further understand the important role of lncRNA in disease, open up the field of clinical medical research, and have further guiding significance for our follow-up research.
1. LncRNA and cancer
Cancer-related lncRNA research is the fastest growing and most productive emerging field. The researchers used Arraystar LncRNA chip to conduct more in-depth research on the identification, occurrence, development, deterioration and metastasis of different cancers, and guided the research direction for establishing a complete methodology system for lncRNA research in other fields.
Cell's latest article on the use of Arraystar LncRNA chip to study breast cancer Â
Cancer Cell's latest article on the use of Arraystar LncRNA chip to study liver cancer Â
Sun Yat-sen University uses LncRNA chip to study the mechanism of lncRNA in children with acute lymphoblastic leukemia
2. LncRNA and cardiovascular and cerebrovascular diseases
Cardiovascular and cerebrovascular diseases and related metabolic diseases are a type of disease that seriously threatens the health of modern people. Using clinically common samples such as cells, blood vessels, and plasma, the researchers used Arraystar LncRNA chips to conduct pioneering research on these diseases.
Circulation Research's latest article on the use of Arraystar LncRNA chips to study circulating biomarkers
Cell Sub-Newsletter Published Arraystar LncRNA Chip to Study Metabolism Related Articles
3. LncRNA and other diseases
Using clinical samples from different diseases, the researchers used Arraystar LncRNA microarray to screen for changes in the characteristic lncRNA expression profile of the disease, suggesting that lncRNA has a wide and important clinical application value, providing a strong clinical basis for the in-depth study of lncRNA.
Cell's latest publication on the use of Arraystar LncRNA chips to study host antiviral responses
Arthritis & Rheumatism publishes article on the use of Arraystar LncRNA chip to study osteoarthritis
Int J Biochem & Cell Biol publishes article on cystic fibrosis using the Arraystar LncRNA chip
4. LncRNA and reproduction, development, regeneration
LncRNA is also widely involved in basic biological processes such as growth and development, reproductive health, and tissue regeneration. Based on the results of Arraystar LncRNA chips at different time points, the researchers can further explore the changes in lncRNA expression profiles during biological growth and development, and further reveal the important functions of lncRNA.
BIOLOGY OF REPRODUCTION publishes Arraystar LncRNA chip to study male reproductive articles
Plos One publishes article on the use of Arraystar LncRNA chip to study pre-eclampsia
Hepatology recently published an article on the use of Arraystar LncRNA chip to study liver regeneration
5. LncRNA and drugs
Drug-related lncRNA research is a very important research field with great application value. Using Arraystar LncRNA chips, researchers can systematically and comprehensively analyze the pharmacology, toxicology, addiction, and safety assessment of drugs to provide a reliable guarantee for human health.
National Laboratory of Biotherapy in Sichuan University uses LncRNA chip to analyze cocaine addiction mechanism
Biochemical Pharmacology publishes Arraystar LncRNA chip to reveal TSA anticancer mechanism
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About Kang Cheng
Kangcheng Bio-engineering Co., Ltd. ("Kangcheng Bio-") has been focusing on high-throughput screening experimental services since 2002. It is one of the earliest high-tech enterprises in China providing professional life science research services. Kangcheng Biotechnology uses lncRNA, microRNA and epigenetics related detection technologies as its core research and development direction. It is a service agent of internationally renowned chip brands such as Agilent, Arraystar, Exiqon and SABiosciences.
Http://
About Kang Cheng
Kangcheng Bio-engineering Co., Ltd. ("Kangcheng Bio-") has been focusing on high-throughput screening experimental services since 2002. It is one of the earliest high-tech enterprises in China providing professional life science research services. Kangcheng Biotechnology uses lncRNA, microRNA and epigenetics related detection technologies as its core research and development direction. It is a service agent of internationally renowned chip brands such as Agilent, Arraystar, Exiqon and SABiosciences.
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